Tag Archives: Ohio State University

Controlling the spread of dog diseases

My comments:

In my experience, the boarding operations and day cares that I and my clients have used have all been diligent about infection control. This isn’t surprising.  Provision of care to multiple dogs in the same environment is their core business and they would be risking their livelihoods and reputation by having an outbreak of disease.

The use, however, of dog parks – at least in Christchurch – seems to be on the rise and this is not always a good thing.  Many of us have experienced dogs that are out of control and owners that don’t seem particularly interested in their responsibilities for picking up poo or training/socialising their dogs.  For this reason, I also question whether or not these owners understand the importance of the core vaccinations along the lines of accepted protocols, or if they recognise when their dog is under the weather.  As the guidelines note, not all diseases are fully preventable with vaccines.

There are only a handful of dogs I have met through my massage courses where the vet has agreed the dog shouldn’t be vaccinated – based on reactions in the past – and have documented this on the dog’s health record.

So, for anyone who organises events with dogs – these guidelines should be useful.  They are geared to North American conditions, but still useful elsewhere.  They are also useful for owners to understand infection control. If you choose to go to events with other animals, reviewing the guidelines and the risk calculator will help you be prepared.

Prevention is better than cure!

Kathleen Crisley, specialist in dog massage, rehabilitation and nutrition/food therapy, The Balanced Dog, Christchurch, New Zealand


Dogs aren’t exactly famous for their personal hygiene or for maintaining a respectful distance from their canine pals. With a nuzzle, a shared ball or a bark, a dog battling a bug can easily pass it to others and, in some cases, people.

dog-play-group

Photo by Ohio State University

This becomes especially worrisome in group settings, such as dog parks, dog shows and doggie daycare, where animals can spread illness rapidly and then carry it back into their homes and neighborhoods. Protocol for keeping disease transmission at bay has, until now, lagged decades behind efforts to contain human infectious disease.

New guidance for halting the spread of a multitude of dog diseases is now available, thanks to an effort led by veterinary experts at The Ohio State University.

The advice, which appears in a user-friendly guide and in a scientific paper in the Journal of the American Veterinary Medical Association, is intended to be a tool for those in charge of canine group settings and for dog owners, said Jason Stull, a veterinarian and assistant professor of veterinary preventive medicine at Ohio State.

“When you have many dogs in a fairly confined space, the opportunities for disease transmission are everywhere,” Stull said.

Stull and his co-authors want their work to lead to written infection prevention and control plans for settings where dogs congregate.

“In veterinary medicine we’re probably 30 years behind in our infection control efforts compared to human medicine,” he said. “But a lot of the risks really can be managed with some simple steps.”

Stull and his collaborators embarked on the effort at the urging of the American Kennel Club. The researchers reviewed more than 400 academic papers related to the topic and examined published reports of outbreaks of disease in dogs before developing their advice.

The guidance they provide is intended to be an outline of the best possible approach to infection control, Stull said.

But what works in one setting won’t necessarily be practical or possible in another and those who make use of it are expected to tailor the guidelines to their needs, he said.

Among the recommendations:

• Dogs with signs of infection should be kept out of group settings.
• People who touch dogs in group settings, such as handlers, staff and judges, should frequently wash their hands or use sanitizer.
• Community surfaces and items should be regularly disinfected and sharing of items such as leashes, toys and bowls should be avoided.
• Dogs should have up-to-date vaccinations, including against distemper, parvovirus, adenovirus, parainfluenza, Bordetella and rabies – all highly contagious diseases that can lead to severe disease and death.
• Efforts should be made to keep rodents and wildlife out of areas where dogs will be, and to keep dogs out of areas most likely to include ticks, fleas and other disease-carrying pests.
• Those in charge of group settings and those who participate should avail themselves of a new online risk calculator to help them determine the potential for disease spread.
• Dogs should be kept clean – and cleaned up after.
• Organizers of group events should avoid overcrowding of dogs.
• Care should be taken with puppies and other dogs with weaker immune systems. The benefits of socialization should be weighed against the risk of illness.
• Every group setting should have on-site or off-site access to a veterinarian who can help with disease-prevention guidelines.

In practice, following this advice could mean a judge uses hand sanitizer between groups of dogs when pulling up their jowls to look at their teeth.

It could mean a parks and recreation department works to eliminate standing water in a dog park, and to stay on top of keeping the grass mowed short.

It could mean a doggie daycare operator assigns dogs to smaller play groups so that if disease spreads it will be limited.

Stull said vaccines are an excellent guard against disease spread, but many of the threats to dog health aren’t vaccine-preventable and require additional thoughtful prevention.

“It’s going to be a bit of a culture change and we need everyone involved – from the dog owners to group organizers to large organizations such as the AKC,” he said.

“People who care about dogs are really invested and want to do what they can to protect their loved ones and that’s what we’re trying to do. On top of that, a lot of these diseases can be transmitted to people.”

Patricia Haines, past president of the Ohio Veterinary Medical Association and a consultant to Stull and his collaborators, said the information they’ve provided is invaluable and science-based.

“This project will be informative to the experts, those planning competitive events and for people who manage private facilities and public situations, such as dog parks,” said Haines, who raises and shows pointers.

“Many of the dog-loving public have never thought of the risks at dog parks and other group settings,” she said.

The new infectious disease guidelines do not focus on animal shelters and rescues, which have other factors to consider and for which there are some existing established recommendations, but rather on settings in which the dogs have owners.

About 35 percent of households in the U.S. and Canada have at least one dog – totaling about 75 million canine companions in North America.

The full report, including the risk calculator and fact sheets addressing particular infectious diseases, are available through the Ohio State College of Veterinary Medicine: http://go.osu.edu/IDk9risk.

Source:  Ohio State University media release

New Cancer Drug for Dogs Also Helps Humans

Dogs suffering from certain types of blood cancers may have a new treatment alternative thanks to the collaborative work of cancer experts looking for options that can help both humans and their pets.

The drug, Verdinexor (KPT-335), works by preventing powerful tumor suppressing proteins from leaving the nucleus of cells, an exodus which allows cancer to grow unchecked. It’s the first new therapeutic option for dog lymphoma in more than two decades, potentially offering vets another alternative for treating the disease, which is the most common form of canine cancer.

“Verdinexor is a really different from chemotherapy, the current standard of care for lymphoma. It works by blocking a protein in the cells responsible for shuttling other proteins in and out of the nucleus, resulting in disruption of cell survival and eventual cell death ,” said veterinary oncologist Cheryl London, DVM, PhD, The Ohio State University College of Veterinary Medicine, who led preclinical, Phase I and Phase II studies of Verdinexor. “Verdinexor could give veterinarians another option if first-line chemotherapy fails or as a potent adjunctive therapy.”

Lead researcher Cheryl London with her dog, photo courtesy of The Ohio State University College of Veterinary Medicine

Lead researcher Cheryl London with her dog, photo courtesy of The Ohio State University College of Veterinary Medicine

“A cancer diagnosis is tough on dogs and their owners. Dogs with lymphoma must go to a veterinary office weekly to receive chemotherapy infusions,” said London. “Since Verdinexor is a pill that can be given at home, it could help make treatment less traumatic for everyone.”

The similarities in the ways human and canine cancer drugs are researched and used are not coincidental. Many types of human and canine cancers are identical at both the cellular and molecular levels, making companion animal studies an ideal place to test drive experimental compounds that appear to have anti-cancer characteristics.

When it comes to cancer, dogs and humans have so much in common,” said London. “I think as human medicine becomes more personalized through the use of genomics, I think we’ll see the same happening in vet medicine.”

Source:  Newswise media release

When something isn’t right with your senior dog

Old dog_dementiaWe love them to bits.  And gradually we notice changes that signal they are getting older.  They may no longer hear the doorbell and, thanks to this new deafness, they may sleep very deeply.

But  changes in an old dog need to be considered carefully.  Behavioral changes can often be the signs of other problems, like diabetes, hypothyroidism or hyperthyroidism, dental disease, and cancers.

One thing that I’m learning more about is canine cognitive dysfunction syndrome (CDS).  Veterinarians describe this as a ‘diagnosis of exclusion’ which means they look to diagnose another disease or disorder first before deciding that the dog is suffering from CDS.

When assessing for symptoms and severity of CDS, veterinarians follow the acronym DISHA.  DISHA stands for:

D= Disorientation

I = Interaction changes

S = Sleep/wake cycle changes

H = House soiling

A = Activity level changes

Disorientation can present as changes in spatial awareness, loss of ability to navigate around familiar obstacles, and/or wandering behavior.

Interaction changes can include a decreased interest in social interaction, petting, greetings, or dependent behaviors.

Restlessness or frequent waking during the night, panic or panting (particularly at night), and increased sleep during the daytime are indications of changes to sleep/wake cycles.

House soiling can increase when there is a loss of signal from the brain so your dog doesn’t realise it needs to eliminate; signs of incontinence or fouling indoors when this has never been a problem are symptoms.

Changes in activity can include decreased exploration and response to stimuli, decreased grooming, change in appetite, increased anxiety with signs of restlessness or agitation and/or separation anxiety.

Most vets offer senior wellness checks  for older dogs.  It’s well worth observing your older pet and discussing all changes with your vet before dismissing the changes as simply old age.

Source:  Ohio State University College of Veterinary Medicine