Category Archives: research

Domestication of dogs and the culling of mammoths

Adjunct Professor at Penn State, Pat Shipman, believes that the abrupt appearance of large numbers of dead mammoths may have been caused by early humans hunting with the first domesticated dogs.

Spectacular archaeological sites yielding stone tools and extraordinary numbers of dead mammoths — some containing the remains of hundreds of individuals — suddenly became common in central and eastern Eurasia between about 45,000 and 15,000 years ago, although mammoths previously had been hunted by humans and their extinct relatives and ancestors for at least a million years.

A fragment of a large bone, probably from a mammoth, Pat Shipman reports, was placed in this dog's mouth shortly after death. This finding suggests the animal was according special mortuary treatment, perhaps acknowledging its role in mammoth hunting. The fossil comes from the site of Predmosti, in the Czech republic, and is about 27,000 years B.P. old. This object is one of three canid skulls from Predmosti that were identified as dogs based on analysis of their morphology. Photo credit: Anthropos Museum, Brno, the Czech Republic, courtesy of Mietje Germonpre.

A fragment of a large bone, probably from a mammoth, Pat Shipman reports, was placed in this dog’s mouth shortly after death. This finding suggests the animal was according special mortuary treatment, perhaps acknowledging its role in mammoth hunting. The fossil comes from the site of Predmosti, in the Czech republic, and is about 27,000 years B.P. old. This object is one of three canid skulls from Predmosti that were identified as dogs based on analysis of their morphology. Photo credit: Anthropos Museum, Brno, the Czech Republic, courtesy of Mietje Germonpre.

“One of the greatest puzzles about these sites is how such large numbers of mammoths could have been killed with the weapons available during that time,” Shipman said.

Surprisingly, Shipman said, she found that “few of the mortality patterns from these mammoth deaths matched either those from natural deaths among modern elephants killed by droughts or by culling operations with modern weapons that kill entire family herds of modern elephants at once.” This discovery suggested to Shipman that a successful new technique for killing such large animals had been developed and its repeated use over time could explain the mysterious, massive collections of mammoth bones in Europe.

The key to Shipman’s new hypothesis is recent work by a team led by Mietje Germonpré of the Royal Belgian Institute of Natural Sciences, which has uncovered evidence that some of the large carnivores at these sites were early domesticated dogs, not wolves as generally had been assumed. Then, with this evidence as a clue, Shipman used information about how humans hunt with dogs to formulate a series of testable predictions about these mammoth sites.

Shipman’s research has been published in the journal Quaternary International and is entitled “How do you kill 86 mammoths?”

For more information about this research and related studies, read the full Penn State media statement.

Your dog’s behaviour – what does it say about your relationship?

Research by Christy L Hoffman of Canisius College in New York indicates that the bond between you and your dog may be the key to their behaviour.

Photo courtesy of Canisius College

Photo courtesy of Canisius College

Methodology

The study looked at human-animal attachment among 60 dog-owning families, including parents and children.  Participants completed questionnaires that asked about their attachment to their pet dogs, their levels of responsibility for the animals, such as feeding and walking them, and their general attitudes toward pets. Participants were also asked to rate their dogs on behavioral characteristics, including excitability, trainability, stranger fear and aggression, separation problems and attention-seeking behavior.

Findings

  • Those individuals who had more positive feelings about pets, in general, and who took more responsibility for the care of their dogs, compared to others in their families, had higher attachments to their dogs. (Probably not a huge surprise to most of us).
  • Owners, regardless of gender, age or race, had a greater attachment to their dogs when the animals scored high on trainability and separation-related problems. In other words, if the dog is well-behaved and likes to socialize with humans, then the bond between the dog and its owner is greater.
  • The more dogs demonstrate attention-seeking behavior with their adult owners, the more attached these owners are likely to be with their dogs. Interestingly, however, this made no difference to the children in the study.

Hoffman thinks that the last finding is indicative of adults having busy lives with parental and work responsibilities – so they are most likely to bond with dogs that seek out their attention.

This research was a collaboration with researchers from the University of Chicago and the University of Pennsylvania and has been published in the  the journal  Human-Animal Interaction Bulletin.

Source:  Canisius College media release

Urine may be the saviour of wild dog populations

Africa’s endangered wild dogs are very clever:  no traditional fence can keep them out.  A doctoral researcher at the Norwegian University of Science and Technology (NTNU), Craig R. Jackson, has explored ways to save the species.

Photo by Craig R. Jackson

Photo by Craig R. Jackson

African wild dogs are a distinct species that cannot inter-breed with other dogs.   The populations of these dogs were in good shape until a few decades ago. In the middle of the last century, there were 500,000 of them in 39 countries. But the species is in decline across nearly its entire range south of the Sahara. Today there are somewhere between 3000 and 5500 left, in fewer than 25 countries. That’s roughly one per cent remaining – and that’s the best case scenario.

Wild dog packs are loath to intrude into the territories of other packs. These territories are defined by urine scent trails. So the researchers and their colleagues collected sand that had been sprayed with urine by wild dogs and moved it near to other packs to keep them inside a certain area – with success.

The use of the scent markings helps to keep wild dogs out of areas where they think there are other dog packs.  But, collection of the urine needed for the scent trails is a problem.  So the next step is re-creating the urine artificially.

The conclusion of the thesis:  urine may be the best bet for saving the African wild dog population; that urine may have to be artificially produced.

Source:  NTNU media release

 

Diagnosis and treatment of bladder cancer in dogs

Veterinary researchers at Oregon State University have identified a unique group of proteins that indicate the presence of transitional cell carcinoma – the most common cause of bladder cancer – and may lead to a new assay which could better diagnose this disease in both dogs and humans.

Photo by Shay Bracha, Oregon State University

Photo by Shay Bracha, Oregon State University

Sheepdogs, collies, and terriers seem particularly susceptible to this type of cancer.  By the time the cancer is diagnosed, it is usually too late to save the dog’s life.

An improved assay to detect this serious disease much earlier in both animals and humans should be possible, scientists said, and may even become affordable enough that it could be used as an over-the-counter product to test urine, much like a human pregnancy test. Some of the work may also contribute to new therapies, they said.

“Research of this type should first help us develop a reliable assay for this cancer in dogs, and improve the chance the disease can be caught early enough that treatments are effective,” said Shay Bracha, an assistant professor in the OSU College of Veterinary Medicine.

Source:  Oregon State University media statement

 

Does your dog disturb your sleep?

Daisy bed photo

While countless pet owners peacefully sleep with a warm pet nearby, a new Mayo Clinic study, presented this week at the 29th Annual Meeting of the Associated Professional Sleep Societies, finds an increase in the number of people experiencing sleep disturbances because of their pets.

A previous Mayo Clinic study published in 2002 reported that of patients who visited the clinic’s sleep center and owned pets, only one percent reported any inconvenience from their pets at night. The new study shows a larger number of patients — 10 percent in 2013 — reported annoyance that their pets sometimes disturbed their sleep.

“The study determined that while the majority of patients did not view their pets intolerably disturbing their sleep, a higher percentage of patients experienced irritation — this may be related to the larger number of households with multiple pets,” says Lois Krahn, M.D., Mayo Clinic psychiatrist and author of the study. “When people have these kinds of sleep problems, sleep specialists should ask about companion animals and help patients think about ways to optimize their sleep.”

Between August and December 2013, 110 consecutive patients at the Mayo Clinic Center for Sleep Medicine in Arizona provided information about pets at night as part of a comprehensive sleep questionnaire. Questions covered the type and number of pets, where the animals slept, any notable behaviors and whether the patient was disturbed. The survey showed that 46 percent of the patients had pets and 42 percent of those had more than one pet. The most popular pets were dogs, cats and birds.

The disturbances by pets that patients reported included snoring, whimpering, wandering, the need to “go outside” and medical needs.

Source:  Newswise press release

A vaccine for canine osteosarcoma?

Osteosarcoma is a highly aggressive bone tumor that affects at least 10,000 dogs annually in the United States, alone.

Photo by osteosarcomaindogs.org

Photo by osteosarcomaindogs.org

It is estimated that 90-95 percent of canine osteosarcoma subjects have microscopic metastatic disease (spread of cancer cells to other parts of the body at the time of diagnosis). Standard of care includes removal of the primary tumor—usually by amputation—followed by chemotherapy. Systemic chemotherapy given after amputation delays the development of metastatic disease; however, despite treatment, most dogs die of the disease within one year of diagnosis.

A new option may be available in the future if Dr. Nicola Mason’s research at the University of Pennsylvania School of Veterinary Medicine produces satisfactory results. Mason, an assistant professor of medicine and a Board-certified ACVIM Diplomate in Small Animal Internal Medicine, is evaluating the first vaccine for canine osteosarcoma.

The approach harnesses the power of the dog’s immune system, “training” it to seek out and destroy cancer cells that remain after amputation and chemotherapy.

Over a century ago, an orthopedic surgeon named William Coley recognized that human sarcoma patients with concurrent bacterial infections that caused high fevers had improved overall survival times compared to those sarcoma patients without infection. This led him to develop a therapeutic concoction of live bacteria that he injected into patients with bone sarcomas. He documented improved survival and in some cases, complete remission in individuals with the aggressive disease by using this early form of “immune therapy.”

Mason’s team is employing similar immune therapeutic strategy to treat dogs with osteosarcoma that have undergone the standard of care treatment (amputation and chemotherapy) to prevent metastatic disease. “The concept is that administration of the Listeria-based (genetically modified bacteria) vaccine will activate the patient’s immune system and educate it to recognize cells that express the target molecule,” says Mason.

Dogs are given the live bacterial vaccine intravenously, Mason explains, and it induces a mild transient fever on the day of vaccination. The dogs are usually treated as outpatients and return home the same day. “We have found highly encouraging results when the vaccine is given to patients that have no evidence of metastatic disease at the time of the study enrollment, which is three weeks after the last chemotherapy is administered. Four out of the first five dogs vaccinated are alive at least two years after their initial diagnosis, which is more than twice their expected survival duration. The vaccine has not yet shown any serious short- or long-term side effects, either.”

Mason says the results have led researchers to evaluate whether this vaccine may be able to directly target and kill the bone tumor itself, perhaps eliminating the need for amputation in the future.

Source:  American College of Veterinary Internal Medicine media release

A new use for Border Collies

Researchers from Central Michigan University presented their research at the annual meeting of the American Society for Microbiology this week.

They’ve found that Border Collies are effective at reducing seagull congregation on recreational beaches, resulting in lower E. coli abundance in the sand

A Border Collie on beach patrol, photo by Elizabeth Alm

A Border Collie on beach patrol, photo by Elizabeth Alm

Gull droppings may be one source of the indicator bacterium Escherichia coli to beach water, which can lead to swim advisories and beach closings. In addition, gull droppings may contain bacteria with the potential to cause human disease, according to Elizabeth Alm, one of the researchers on the study.

At the beginning of the summer, 200-meter sections of beach were arbitrarily assigned to be dog-treated beaches or control beaches. Half way through the summer, the beach sections were swapped, so that dogs were moved to the control beaches and the dog-treated beaches were then left to be untreated controls.

During the summers of 2012 and 2013, researchers recorded the number of gulls at each beach section. Once each week samples of beach water and beach sand were collected and the numbers of E. coli in the samples counted. In early summer, samples from beaches where dogs had excluded gulls had significantly lower E. coli counts compared to control beaches.

“Border collies are intelligent dogs that love to work and could be used by beach managers as part of a comprehensive management strategy to reduce bacterial contamination at public beaches,” said Alm.

Source:  American Society for Microbiology media release

 

Albino Dobermans

Michigan State University researchers have identified a genetic mutation in Doberman pinschers that causes albinism in the breed, a discovery that has eluded veterinarians and breeders worldwide up until now.

Michigan State University photo

Michigan State University photo

Paige Winkler, a doctoral student at the College of Veterinary Medicine, says that the researchers found a gene mutation that results in a missing protein responsible for the pigmentation of cells.

Albino Dobermans possess a pink nose, white or very light colored coats, and pale irises in the eyes.  These characteristics are similar to human albinos who have light skin, eye discoloration and often experience visual problems.

Like human albinos, the albino Dobermans are sensitive to light and have an increased risk of skin tumors.

Winkler says that this discovery will help Doberman breeders in the future where breeding lines carrying the defective gene can be identified.

Source:  Michigan State University media statement

Behavioural problems in pet store dogs

Dogs purchased from pet stores are more likely to have a range of behavior problems than those purchased from small, non-commercial breeders, says a study by researchers at the Best Friends Animal Society and the University of Pennsylvania School of Veterinary Medicine.

The study was published in the Journal of the American Veterinary Medical Association.

The study involved 413 dogs purchased from pet stores.  Psychological and behavioral characteristics of these dogs were compared to the same characteristics in 5,657 dogs obtained from small-scale, private breeders.  (Most puppies sold in pet stores in the USA are sourced from large-scale, puppy mill type commercial breeders).

Results show that dogs obtained as puppies from pet stores showed significantly more aggression toward human family members, unfamiliar people and other dogs. Dogs purchased from pet stores were almost twice as likely to exhibit aggression directed toward unfamiliar dogs than dogs purchased from small non-commercial breeders.

The pet store dogs also a displayed greater fear of other dogs and typical events in pet dogs’ lives, had more behavior problems when left alone at home, and experienced more problems with house-soiling.  These behaviors in young adult dogs are reasons typically cited by people who surrender their pets to animal shelters.

“The results were so one-sided that in the wide range of behavior problems we included in our analysis, pet store dogs failed in every single case to even obtain one more favorable score than the comparison group of dogs” says Dr Frank McMillan of Best Friends Animal Society.

The research team acknowledges that the exact causes of the behavioral problems observed are not known; until these causes are understood, they recommend avoiding purchasing puppies from pet stores.

Source:  BusinessWire media release

See my related post about the ASPCA’s No Pet Store Puppies initiative

 

 

 

Dogs benefit children with autism

A University of Missouri researcher has studied dog ownership decisions in families of children with autism and found that parents report a range of benefits of dog ownership including companionship, stress relief and opportunities for their children to learn responsibility.

Photo credit: Noël Zia Lee, Wikimedia Commons

Photo credit: Noël Zia Lee, Wikimedia Commons

‘Children with autism spectrum disorders often struggle with interacting with others, which can make it difficult for them to form friendships,’ said Gretchen Carlisle, the study’s author. ‘Children with autism may especially benefit from interacting with dogs, which can provide unconditional, nonjudgmental love and companionship to the children.’

Carlisle interviewed 70 parents of children with autism.  Nearly two-thirds of the parents in the study owned dogs, and of those parents, 94 percent reported their children with autism were bonded to their dogs. Even in families without dogs, 70 percent of parents said their children with autism liked dogs.

‘Bringing a dog into any family is a big step, but for families of children with autism, getting a dog should be a decision that’s taken very seriously.  If a child with autism is sensitive to loud noises, choosing a dog that is likely to bark will not provide the best match for the child and the family. If the child has touch sensitivities, perhaps a dog with a softer coat, such as a poodle, would be better than a dog with a wiry or rough coat, such as a terrier.’

The study, “Pet Dog Ownership Decisions for Parents of Children With Autism Spectrum Disorder,” was published in the Journal of Pediatric Nursing earlier this year.

Source:  University of Missouri media release

For more about the benefits of dogs for people with autism, read my post Dogs are a ‘social lubricant’ in helping people with autism