Author Archives: DoggyMom.com

Risk factors for bone cancer in dogs

Bone cancer in dogs is affected by a variety of genetic risk factors, researchers from Uppsala University and the Broad Institute have found.  They’ve published their results in the journal Genome Biology.
Osteosarcoma, a type of bone cancer, is similar in humans and dogs – although in dogs it is more common.  In the current study, the researchers compared the genome of sick and healthy dogs from three different breeds to find inherited risk factors for the disease.

“The key is that we find many different risk factors within each breed. We already knew that Greyhounds, Rottweilers and Irish wolfhounds are at increased risk of developing bone cancer and our results explain much of the increased risk”, said Emma Ivansson, scientist at SciLifeLab and Uppsala University.

Irish Wolfhound

The study demonstrated that each breed has its own risk genes, but these genes converge in common disease mechanisms.

“Our results show that the pathways involved in bone formation and growth are important for the disease. Because of the great similarities between bone cancer in dogs and humans, we believe that our findings may contribute to an increased understanding of how bone cancer develops in humans”, said Kerstin Lindblad-Toh, professor at Uppsala University and Co-Director of the SciLifeLab and Director of Vertebrate Genome Biology at the Broad Institute.
The researchers are continuing to study the identified risk factors to understand more about how they affect tumor development and to see whether different risk factors respond to different types of treatment.
The researchers are continuing to study the identified risk factors to understand more about how they affect tumor development and to see whether different risk factors respond to different types of treatment. – See more at: http://www.uu.se/en/media/news/article/?id=3103&area=2,10,16&typ=artikel&na=&lang=en#sthash.H1aUoBA8.dpuf

Osteosarcoma, a type of bone cancer, is a rare but very aggressive form of cancer that primarily affects teenagers. Among some large-sized dog breeds the disease is much more common, but otherwise osteosarcoma in humans and dogs is very similar. In the current study, the researchers compared the genome of sick and healthy dogs from three different breeds to find inherited risk factors for the disease.

“The key is that we find many different risk factors within each breed. We already knew that greyhounds, Rottweilers and Irish wolfhounds are at increased risk of developing bone cancer and our results explain much of the increased risk”, said Emma Ivansson, scientist at SciLifeLab and Uppsala University.

The study demonstrated that each breed has its own risk genes, but these genes converge in common disease mechanisms

– See more at: http://www.uu.se/en/media/news/article/?id=3103&area=2,10,16&typ=artikel&na=&lang=en#sthash.H1aUoBA8.dpuf

Bone cancer in dogs is affected by a variety of genetic risk factors. Researchers from Uppsala University and the Broad Institute show this in a new study published in Genome Biology. – See more at: http://www.uu.se/en/media/news/article/?id=3103&area=2,10,16&typ=artikel&na=&lang=en#sthash.H1aUoBA8.dpuf

Beefcake (not beef bones) to benefit dogs

Christchurch based animal welfare charity K9 Rescue and Rehoming has paired well-muscled men with dogs available for adoption in their 2014 calendar.

K9 Rescue and Rehoming calendar

Entitled Dogs and Dudes, this fundraising calendar includes photographs of New Zealand actors and other local celebrities who were willing to bare their bodies to support dog adoption.

The best way to organise a purchase is to contact Trisha through the organisation’s Facebook page.  Calendars cost NZ$25

And dog owners get to enjoy a little beefcake all year long, combined with some really beautiful dog photos, too!

Breast cancer in dogs

A PhD project at the Norwegian School of Veterinary Science has been studying the genetics behind mammary tumours in dogs.  Breast cancer is the most common form of cancer in female dogs.

A mammary tumor in a dog (Photo by Veronica Kristiansen)

A mammary tumour in a dog (Photo by Veronica Kristiansen)

Kaja Sverdrup Borge’s PhD project has led to the identification of genetic changes associated with these types of tumour.

Borge studied known risk genes in dogs to learn more about the genes that predispose dogs to canine mammary tumours. These genes are already known to be linked to cancer in humans. Borge discovered that there was a large variation in these genes from breed to breed. Some of the variants proved to have a detrimental effect and could lead to a potential change in the risk of developing cancer.

Borge compared the incidence of these genes in different groups of English springer spaniels with and without mammary tumours. The genes were also studied in another group of dogs from breeds having either a high or low incidence of mammary tumours. The results of these analyses indicate that variants of the oestrogen receptor gene are associated with the risk of English springer spanieldeveloping mammary tumours in dogs.

Borge examined canine mammary tumours in order to identify mutations which have arisen in tumours and may therefore be involved in the development of cancer. She focused on changes in the number of gene copies where there was either a decrease or increase in gene areas in the tumours.

She found a large number of mutations and the number of aberrations increased, the more malignant the tumours turned out to be. She detected major cancer genes known to occur in humans but also identified new areas. Borge also demonstrated that linking detailed histopathological parameters from mammary tumour diagnostics to genetic mutations could help to chart specific genes that lead to the growth of tumours and to more malignant types of cancer.

Increased knowledge about the genetic changes which cause cancer is essential for the prevention, diagnosis and treatment of the disease.  Because of the similarities between carcinogenic gene mutations in both canine and human breast cancer, studying breast cancer in dogs also has benefits for the study of breast cancer in humans.

Source:  Media statement from Norwegian School of Veterinary Science

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Wordless Wednesday, part 14

Stretching dog

The ability for dogs and wolves to learn

Wolves can learn from observing humans and pack members where food is hidden and recognize when humans only pretend to hide food, reports a study published for the first time in the open-access journal Frontiers in Psychology.

The researchers conclude that the ability to learn from other species, including humans, is not unique to dogs but was already present in their wolf ancestors. Prehistoric humans and the ancestors of dogs could build on this ability to better coordinate their actions.  Photo by Wolf Science Center

The researchers conclude that the ability to learn from other species, including humans, is not unique to dogs but was already present in their wolf ancestors. Prehistoric humans and the ancestors of dogs could build on this ability to better coordinate their actions. Photo by Wolf Science Center

These findings imply that when our ancestors started to domesticate dogs, they could have built on a pre-existing ability of wolves to learn from others, not necessarily pack members.

A paper published recently in the journal Science suggested that humans domesticated dogs about 18 thousand years ago, possibly from a European population of grey wolves that is now extinct. But it remains unknown how much the ability of dogs to communicate with people derives from pre-existing social skills of their wolf ancestors, rather than from novel traits that arose during domestication.

In a recent study, Friederike Range and Zsófia Virányi from the Messerli Research Institute at the University of Veterinary Medicine Vienna investigated if wolves and dogs can observe a familiar “demonstrator” – a human or a specially trained dog – to learn where to look for food within a meadow. The subjects were 11 North American grey wolves and 14 mutts, all between 5 and 7 months old, born in captivity, bottle-fed, and hand-raised in packs at the Wolf Science Center of Game Park Ernstbrunn, Austria.

The wolves and dogs were two to four times more likely to find the snack after watching a human or dog demonstrator hide it, and this implies that they had learnt from the demonstration instead of only relying on their sense of smell. Moreover, they rarely looked for the food when the human demonstrator had only pretended to hide it, and this proves that they had watched very carefully.

The wolves were less likely to follow dog demonstrators to hidden food. This does not necessarily mean that they were not paying attention to dog demonstrators: on the contrary, the wolves may have been perceptive enough to notice that the demonstrator dogs did not find the food reward particularly tasty themselves, and so simply did not bother to look for it.

Source:  EurekAlert! press release

Why breed specific legislation does not protect the public from dangerous dogs

Photo courtesy of University of Lincoln (UK)

Photo courtesy of University of Lincoln (UK)

The latest research on breed specific legislation formalises a lot of the information that I already suspected or knew from other sources:  that BSL doesn’t work and is a flawed concept.    Read more below:

Research conducted by animal behaviour experts challenges the basis of breed specific legislation designed to protect the public from ‘dangerous’ dogs.

A team from the University of Lincoln, UK, concluded that rather than making people safer, current legislation could be lulling them into a false sense of security. Their findings were recently published in the journal Human Animal Interaction Bulletin published by the American Psychological Association, in a freely available paper “Acculturation – Perceptions of breed differences in behavior of the dog (Canis familiaris)”.

Dr Tracey Clarke and Professors Daniel Mills and Jonathan Cooper from Lincoln’s School of Life Sciences set out to discover the source of people’s perceptions about ‘typical behaviours’ associated with different breeds of dog.

Professor Mills said: “This work provides good scientific evidence to explain why the pursuit by governments of breed specific legislation to reduce the risk of harm to citizens is not only doomed to failure, but also giving people a false sense of security, which may actually be making the situation worse.”

The researchers applied a theory known as the ‘contact hypothesis’ – used by sociologists to understand the origin of racial stereotyping and other forms of prejudice.

They surveyed more than 160 people to examine if their contact with dogs influenced their tendency to believe populist and negative breed stereotypes.

They found significant variations in attitudes between people who owned dogs or had regular contact with them, and those who did not. More than half (54%) of respondents who identified themselves as “experienced or knowledgeable” of dogs disagreed with the statement that some breeds are more aggressive than others. Only 15% of respondents who said they had little or no experience of dogs held the same view.

Similarly, more than half of the “experienced” respondents felt there was no valid reason for breed specific legislation, whereas less than 1 in 10 of the inexperienced respondents felt the same.

The results were consistent with the prediction that not just the level but also the quality of contact with dogs are major influences on the tendency to believe populist breed stereotypes, despite scientific evidence which challenges the validity of such generalisations.

The variability within a breed is nearly always greater than the variability between breeds for behavioural traits, meaning while there may be differences on average, when it comes to assessing the likelihood that a particular individual will behave in a certain way generalisations are often unsound. The type of person attracted towards certain breeds and encouraging certain behaviours may be a much better predictor.

It was discovered that a dog’s visible characteristics informed strong attitudes, resulting in over-generalisation. Not only bull-breeds but also those with much more superficial characteristics such as being well-muscled, or even short-haired, were stigmatised more often as dangerous by those with less experience or knowledge of dogs.

Attraction to certain types on the basis of their appearance, can then lead to these being preferred for use as a weapon or status dog, creating a self-fulfilling prophecy about their behaviour through environmental rather than genetic effects.

The team suggest that further scientific research is needed to improve understanding of the origins and basis of negative breed stereotypes, and that this in turn should be used to inform future legislation.

Source:  University of Lincoln media statement

7 Steps to a Happier Pet

This holiday season, the Humane Society of the United States would like to share its 7 steps to a happier pet:

  1. Make sure your pet wears an identification tag
  2. Make sure you enroll your new puppy in behavioural training classes to prevent problems
  3. Animal behavioural problems can be health-related.  Make sure your pet has a complete medical exam by a veterinarian at least once a year
  4. Prepare for disasters and make sure you have a plan for your pet in the event of a hurricane, tornado, fire, flood or earthquake
  5. Plan for your pet’s future in case something happens to you
  6. Learn how to prevent dog bites and how to prevent your dog from biting; visit the Humane Society’s website.
  7. Have a heart, be smart, and make sure your pet is spayed or neutered.
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Wordless Wednesday, part 13

Counter surfing dog

Rin Tin Tin: The Life and the Legend

rin tin tin book cover

I have just finished reading Rin Tin Tin:  The Life and the Legend by Susan Orlean.  Having previously blogged about the Dogs on the Hollywood Walk of Fame, I was intrigued when this book made the New York Times bestseller list.

If you like biography, you will like this book.  It has been expertly researched by Orlean who spent weeks reviewing the archived personal files of Lee Duncan, the owner and trainer of the original Rin Tin Tin.  Duncan fought in France during WWI and found the young ‘Rinty’ in an abandoned kennels.  He was able to secret Rin Tin Tin away on a ship returning servicemen to the United States along with his sister, who unfortunately died shortly after arriving in the USA.

Duncan bonded with the dog like no other individual (human or otherwise) in his life and found the dog exceptionally bright (although cranky with other humans).  In the 1920s, he was certain that Rinty was movie material.  Orlean does a superb job describing old Hollywood – before sound was even introduced to films and Duncan’s efforts to make his dog a film star.

Rin Tin Tin’s popularity is the main reason why German Shepherd dogs became a popular breed in the United States.

During this period in American history, dog training was not even recognised as a discipline.  In large part thanks to Rin Tin Tin’s popularity, the benefits of dog training were introduced to the American public.  Orlean again does a superb job in explaining how trained dogs were exhibited to Americans as entertainment, eventually spawning an entire industry.

It is very entertaining to read about Rin Tin Tin’s early success and the challenges posed by the introduction of sound to the movies.  Duncan, perhaps in denial, didn’t make provisions for a successor to Rin Tin Tin and – as was inevitable – the original Rinty died.  Rinty’s son was not up to scratch for acting duties and there was a time before a suitable successor was trained.

From there, the story becomes one of how Rin Tin Tin became a legend and an industry.   Other dogs, including subsequent descendents, take on the role of Rin Tin Tin and he is even transformed to a television star in the Adventures of Rin Tin Tin.  At this point, there are spin-off benefits of merchandising.

So many people invested emotional energy (as well as lots of money) in keeping Rin Tin Tin in front of the American public, well into the 1970s.  By the 1980s, however, American tastes had changed.

This book is well written and with a good pace throughout.  I recommend it  particularly if you have a German Shepherd in your life, or someone who is a German Shepherd fan, this book would make an excellent Christmas gift.

Doggy quote of the month for December

“If you want the best seat in the house, move the dog”

– Unknown

New settee